Otologic Wegener's granulomatosis.
نویسندگان
چکیده
Wegener’s granulomatosis (WG) is a systemic vasculitic disease characterized by necrotizing granulomas and vasculitis of small vessels.1,2 Upper airway tract involvement is frequent over the course of the disease.1,3 Cytoplasmatic pattern antineutrophil cytoplasmic antibodies (c-ANCA) are highly specific for WG in the active phase.1,3 Proteinase 3-ANCA (PR3-ANCA) positivity is usually associated to progression from localized to systemic disease.2
منابع مشابه
Wegener's granulomatosis presenting with otologic manifestations.
1. Cotch MF, Hoffman GS, Yerg DE, Kaufman GI, Targonski P, Kaslow RA. The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources. Arthritis Rheum. 1996;39(1):87-92. 2. McDonald TJ, Deremee RA. Wegener's granulomatosis. Laryngoscope. 1983;93(2):220-31. 3. Fauci AS, Haynes BF,...
متن کاملPatterns of presentation and diagnosis of patients with Wegener's granulomatosis: ENT aspects.
DESIGN a cross-sectional study. PARTICIPANTS One hundred and ninety-nine patients with Wegener's granulomatosis belonging to a patient self-help group. MAIN OUTCOME MEASURES Mode of initial presentation; diagnosis timescales and delay; rhinologic involvement; and treatment. RESULTS Sixty-three per cent of patients initially presented with ENT-related symptoms. Ninety-two per cent faced a ...
متن کامل[The otologic manifestation of Wegener's granulomatosis--review of contemporary achievements in diagnostics and treatment].
OBJECTIVE Wegener granulomatosis (WG) presents nasal, laryngeal and otologic symptoms as an initial signs of the disease and finally can affect the ENT region in 3/4 patients. The authors want to analyze 7 cases of WG with early aural symptoms, connected with the diagnostics dilemma, discuss the problems of otologic manifestation in WG and present the newest concepts of diagnostics and treatmen...
متن کاملOtologic Manifestations and Progression in Patients with Wegener’s granulomatosis: A Survey in 55 Patients
Introduction Granulomatosis with polyangiitis (GPA; also known as Wegener's granulomatosis) is a primary systemic vasculitis involving the ear, nose and throat system (ENT) and lower respiratory tract. Because of the lack of knowledge regarding the clinical findings of GPA due to the limited number of studies, the current study was designed to investigate the prevalence and nature of the otolog...
متن کاملBasilar artery occlusion in a young patient with Wegener's granulomatosis.
BACKGROUND AND PURPOSE Stroke is an uncommon sequela of Wegener's granulomatosis, resulting primarily from vasculitic infiltration of small to medium-sized vessels. We describe a young patient with Wegener's granulomatosis and basilar artery occlusion. CASE DESCRIPTION A 26-year-old man with histopathologically confirmed Wegener's granulomatosis suffered a brain stem stroke 24 hours after ope...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Acta otorrinolaringologica espanola
دوره 64 6 شماره
صفحات -
تاریخ انتشار 2013